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. 2010-01-01. In a new era of environmental awareness and citizen participation in government.

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Veterinary Microbiology, Third Edition is organized into four sections and begins with an updated and expanded introductory section on infectious disease pathogenesis, diagnosis and clinical management. The second section covers bacterial and fungal pathogens, and the third section describes viral d. Thompson, David C.; Crampton, Faith E.; Wood, R. Craig 2012-01-01 In the new edition of this essential, all-inclusive text, the authors provide more important research for future principals and others enrolled in graduate-level school finance courses.

Written in a style that is highly readable, the book offers strong connections to real-world experiences. Readers get both a broad overview of funding concepts and. Flanagan, Marian; Christensen, Tina Paulsen 2014-01-01 There is a growing interest in machine translation (MT) and post- editing (PE). MT has been around for decades, but the use of the technology has grown significantly in the language industry in recent years, while PE is still a relatively new task.

Consequently, there are currently no standard PE. Thompson, David C.; Crampton, Faith E.; Wood, R. Craig 2012-01-01 In the new edition of this essential, all-inclusive text, the authors provide more important research for future principals and others enrolled in graduate-level school finance courses. Written in a style that is highly readable, the book offers strong connections to real-world experiences. Readers get both a broad overview of funding concepts and. Christine M Szymanski 2012-02-01 Full Text Available As we commemorate the 30th anniversary of the Campylobacter, Helicobacter and Related Organisms (CHRO workshops with this special Frontiers edition, we look back upon three decades of research and provide some highlights from the 16th International CHRO meeting. As Martin Skirrow noted, Elizabeth King was the first to isolate campylobacters in the 1950’s, although Escherich himself provided drawings of these fecal organisms back in the 1880’s.

Helicobacter is a more recent organism, first described to be the causative agent of stomach ulcers at a CHRO meeting by Barry Marshall and Robin Warren – who then later received the Nobel Prize for their findings that bacteria could cause diseases previously believed to be caused by human factors. Studies of the intersection of host microbial ecology and pathogen infection have been pioneered by scientists such as Brett Finlay, who described his current work on this topic. And as general antibiotics are routinely administered, we see a rise in bacterial antibiotic resistance. Julian Davies emphasized that there is a growing need for the development of new bioactive compounds on the horizon as we advance our knowledge on these pathogens. The first genome of C. Jejuni was published in 2000; now one decade later we have 30 Campyobacter taxa sequenced, and this number continues to rise quickly. However, we continue to obtain unexpected results as a pioneer in CHRO research, Martin Blaser explained – i.e., although H.

Pylori is now classified as a level I carcinogen, there may be benefits to carrying this organism as part of your normal flora. Other findings indicate that Campylobacters and Helicobacters do not follow classic paradigms of other well-characterized gastrointestinal pathogens. And we are learning that there is a whole world of interesting related organisms beyond C. Jejuni and H. This review summarizes some of the history of CHRO research and the exciting directions ahead. Ignasi Vegas Pajaro 2017-01-01 Full Text Available Recording, storing and sharing video content has become one of the most popular usages of smartphones.

This has resulted in demand for video editing apps that the users can use to edit their videos before sharing on various social networks. This study describes a technique to create a video editing application that uses the processing power of both GPU and CPU to process various editing tasks. The results and subsequent discussion shows that using the processing power of both the GPU and CPU in the video editing process makes the application much more time-efficient and responsive as compared to just the CPU-based processing. Eaton, Kenneth A; Pitts, Nigel B 2009-04-01 Over the years, several members of the staff of the Dental Health Services Research Unit (DHSRU) at Dundee have published papers in Primary Dental Care. Furthermore, its Director, Professor Nigel Pitts, together with Drs Jan Clarkson and Gail Topping have co- edited a number of the Faculty of General Dental Practice (UK)'s standards manuals and contributed to others. It had been suggested to the Unit by several parties that, having been in funded existence for some 30 years, it would be appropriate to mark this anniversary with a conference to explore 'Dental Health Services Research: After 30 years, what was the impact, what have we learned and where are we going?'

So, following a range of consultations, the conference was convened at the West Park Conference Centre in Dundee with a mixed audience representing both dental research and dental practice. Bundschuh, Ralf 2012-02-01 The central dogma of molecular Biology states that DNA is transcribed base by base into RNA which is in turn translated into proteins. However, some organisms edit their RNA before translation by inserting, deleting, or substituting individual or short stretches of bases. In many instances the mechanisms by which an organism recognizes the positions at which to edit or by which it performs the actual editing are unknown. One model system that stands out by its very high rate of on average one out of 25 bases being edited are the Myxomycetes, a class of slime molds. In this talk we will show how the computational methods and concepts from statistical Physics can be used to analyze DNA and protein sequence data to predict editing sites in these slime molds and to guide experiments that identified previously unknown types of editing as well as the complete set of editing events in the slime mold Physarum polycephalum.

1999-01-01 During an anniversary banquet honoring the Apollo program team, the people who made the entire lunar landing program possible, former Apollo astronauts Neil Armstrong (left) and Gene Cernan talk about their experiences. The banquet was held in the Apollo/Saturn V Center, part of the KSC Visitor Complex. This is the 30th anniversary of the Apollo 11 launch and moon landing, July 16 and July 20, 1969.

Other guests at the banquet were astronauts Wally Schirra, Edwin 'Buzz' Aldrin and Walt Cunningham. Neil Armstrong was the first man to walk on the moon; Gene Cernan was the last. 1999-01-01 Former Apollo 11 astronaut Neil A. Armstrong stands to a round of applause after being introduced at the anniversary banquet honoring the Apollo team, the people who made the entire lunar landing program possible. The banquet was held in the Apollo/Saturn V Center, part of the KSC Visitor Complex. This is the 30th anniversary of the Apollo 11 launch and moon landing, July 16 and July 20, 1969.

Neil Armstrong was the first man to set foot on the moon. He appeared at the banquet with other former astronauts Edwin 'Buzz' Aldrin, Gene Cernan, Walt Cunningham and others. Editorial Office of Chinese Journal of Chemistry 2010-01-01 @@ May 2010 is the 60th Anniversary of Shanghai Institute of Organic Chemistry(SIOC),Chinese Academy of Sciences(CAS),the founder and sponsor of Chinese Journal of Chemistry(CJC).In China,a cycle of sixty years forms a so called'jiazi(甲子)',which is the Chinese way of counting years.It is the time that signifies the end of an old cycle and the beginning of a new one.This special issue of CJC is dedicated to SIOC for celebrating her 60th anniversary. Jeffrey Brune 2014-01-01 Full Text Available The plenary session at SDS 2013 on “Reflections on the Fiftieth Anniversary of Stigma” marked the fiftieth anniversary of Erving Goffman’s Stigma, which remains one of the most cited and influential works in the field. The panelists, whose essays appear in this forum, discuss Stigma’s origins and uses over the past decades, how the book has affected their own research and understandings of disability, and what role Stigma might play as disability studies continues to evolve. Each of the five essays in its own way answers one central question: whether and how Goffman’s work remains useful as we move the field forward. Jeffrey Brune; Rosemarie Garland-Thomson; Susan Schweik; Tanya Titchkosky; Heather Love 2014-01-01 The plenary session at SDS 2013 on “Reflections on the Fiftieth Anniversary of Stigma” marked the fiftieth anniversary of Erving Goffman’s Stigma, which remains one of the most cited and influential works in the field.

The panelists, whose essays appear in this forum, discuss Stigma’s origins and uses over the past decades, how the book has affected their own research and understandings of disability, and what role Stigma might play as disability studies continues to evolve. Each of the five. Cai Chen Full Text Available RNA editing describes the process in which individual or short stretches of nucleotides in a messenger or structural RNA are inserted, deleted, or substituted. A high level of RNA editing has been observed in the mitochondrial genome of Physarum polycephalum. The most frequent editing type in Physarum is the insertion of individual Cs. RNA editing is extremely accurate in Physarum; however, little is known about its mechanism. Here, we demonstrate how analyzing two organisms from the Myxomycetes, namely Physarum polycephalum and Didymium iridis, allows us to test hypotheses about the editing mechanism that can not be tested from a single organism alone.

First, we show that using the recently determined full transcriptome information of Physarum dramatically improves the accuracy of computational editing site prediction in Didymium. We use this approach to predict genes in the mitochondrial genome of Didymium and identify six new edited genes as well as one new gene that appears unedited. Next we investigate sequence conservation in the vicinity of editing sites between the two organisms in order to identify sites that harbor the information for the location of editing sites based on increased conservation. Our results imply that the information contained within only nine or ten nucleotides on either side of the editing site (a distance previously suggested through experiments is not enough to locate the editing sites.

Finally, we show that the codon position bias in C insertional RNA editing of these two organisms is correlated with the selection pressure on the respective genes thereby directly testing an evolutionary theory on the origin of this codon bias. Beyond revealing interesting properties of insertional RNA editing in Myxomycetes, our work suggests possible approaches to be used when finding sequence motifs for any biological process fails. Chen, Cai; Frankhouser, David; Bundschuh, Ralf 2012-01-01 RNA editing describes the process in which individual or short stretches of nucleotides in a messenger or structural RNA are inserted, deleted, or substituted. A high level of RNA editing has been observed in the mitochondrial genome of Physarum polycephalum. The most frequent editing type in Physarum is the insertion of individual Cs.

RNA editing is extremely accurate in Physarum; however, little is known about its mechanism. Here, we demonstrate how analyzing two organisms from the Myxomycetes, namely Physarum polycephalum and Didymium iridis, allows us to test hypotheses about the editing mechanism that can not be tested from a single organism alone. First, we show that using the recently determined full transcriptome information of Physarum dramatically improves the accuracy of computational editing site prediction in Didymium. We use this approach to predict genes in the mitochondrial genome of Didymium and identify six new edited genes as well as one new gene that appears unedited.

Next we investigate sequence conservation in the vicinity of editing sites between the two organisms in order to identify sites that harbor the information for the location of editing sites based on increased conservation. Our results imply that the information contained within only nine or ten nucleotides on either side of the editing site (a distance previously suggested through experiments) is not enough to locate the editing sites. Finally, we show that the codon position bias in C insertional RNA editing of these two organisms is correlated with the selection pressure on the respective genes thereby directly testing an evolutionary theory on the origin of this codon bias. Beyond revealing interesting properties of insertional RNA editing in Myxomycetes, our work suggests possible approaches to be used when finding sequence motifs for any biological process fails. PMID:22383871. Chen, Cai; Frankhouser, David; Bundschuh, Ralf 2012-01-01 RNA editing describes the process in which individual or short stretches of nucleotides in a messenger or structural RNA are inserted, deleted, or substituted.

A high level of RNA editing has been observed in the mitochondrial genome of Physarum polycephalum. The most frequent editing type in Physarum is the insertion of individual Cs. RNA editing is extremely accurate in Physarum; however, little is known about its mechanism.

Here, we demonstrate how analyzing two organisms from the Myxomycetes, namely Physarum polycephalum and Didymium iridis, allows us to test hypotheses about the editing mechanism that can not be tested from a single organism alone. First, we show that using the recently determined full transcriptome information of Physarum dramatically improves the accuracy of computational editing site prediction in Didymium. We use this approach to predict genes in the mitochondrial genome of Didymium and identify six new edited genes as well as one new gene that appears unedited. Next we investigate sequence conservation in the vicinity of editing sites between the two organisms in order to identify sites that harbor the information for the location of editing sites based on increased conservation. Our results imply that the information contained within only nine or ten nucleotides on either side of the editing site (a distance previously suggested through experiments) is not enough to locate the editing sites.

Finally, we show that the codon position bias in C insertional RNA editing of these two organisms is correlated with the selection pressure on the respective genes thereby directly testing an evolutionary theory on the origin of this codon bias. Beyond revealing interesting properties of insertional RNA editing in Myxomycetes, our work suggests possible approaches to be used when finding sequence motifs for any biological process fails.

2010-01-01 Meinhart, while also acknowledging previous edition contributions from Dr� Lenny Wong, Dr� Craig Bullis, and Colonel (Ret) George Reed� 1 CHAPTER 1.the cyber war� Although the strategies are different between commercial and government entities, at the end of the day both seek competitive.and everyone else—to 140 characters per tweet, and he tweets once or more almost daily�4 400 million people have established accounts on Facebook �5. Wangsness, Roald K. 1986-07-01 This revised edition provides patient guidance in its clear and organized presentation of problems. It is rich in variety, large in number and provides very careful treatment of relativity. One outstanding feature is the inclusion of simple, standard examples demonstrated in different methods that will allow students to enhance and understand their calculating abilities.

There are over 145 worked examples; virtually all of the standard problems are included. Jang, Yoon-Young; Cai, Liuhong; Ye, Zhaohui 2016-01-01 Genome editing is the process in which DNA sequences at precise genomic locations are modified.

In the past three decades, genome editing by homologous recombination has been successfully performed in mouse for generating genetic models. The low efficiency of this process in human cells, however, had prevented its clinical application until the recent advancements in designer endonuclease technologies. The significantly improved genome editing efficiencies aided by ZFN, TALEN, and CRISPR systems provide unprecedented opportunities not only for biomedical research, but also for developing novel therapies. Applications based on these genome editing tools to disrupt deleterious genes, correct genetic mutations, deliver functional transgenes more effectively or even modify the epigenetic landscape are being actively investigated for gene and cell therapy purposes. Encouraging results have been obtained in limited clinical trials in the past two years. While most of the applications are still in proof-of-principle or preclinical development stages, it is anticipated that the coming years will see increasing clinical success in novel therapies based on the modern genome editing technologies.

It should be noted that critical issues still remain before the technologies can be translated into more reliable therapies. These key issues include off-target evaluation, establishing appropriate preclinical models and improving the currently low efficiency of homology-based precise gene replacement. In this review we discuss the preclinical and clinical studies aiming at translating the genome editing technologies as well as the issues that are important for more successful translation. 2001-01-01 Transcripts of typical dicot plant plastid genes undergo C→U RNA editing at approximately 30 locations, but there is no consensus sequence surrounding the C targets of editing. The cis-acting elements required for editing of the C located at tobacco rpoB editing site II were investigated by introducing translatable chimeric minigenes containing sequence –20 to +6 surrounding the C target of editing.

When the –20 to +6 sequence specified by the homologous region pre. (Ed.); Sterken, Christiaan 2012-08-01 New Perspectives on Technical Editing by Avon J.

Murphy (ed.) ISBN: 9949 (2010) Baywood Publishing Company Inc, Hardcover, 210 pages, 35.5 GBP This book presents a collection of 10 chapters dealing with diverse aspects of technical editing (ie, editorial planning, and analysis and structural changes made to other people's technological documents): research in technical editing, trends and teaching of technical editing, copyediting, and technical journal editing. The role and function of the modern journal and book editor is also dealt with in detail. Each chapter is written by an expert in the field: senior editors, university professors in technical communication, technical writers and linguists. The ever-evolving role of the editor is clearly elucidated in several historical reviews, and in the descriptions of the expectations for the future. A very striking aspect of this book is its extensive collection of bibliographic resources: every chapter lists dozens of very useful references, and the closing chapter, and annotated bibliography, contain many not so well known references, and are most useful.

All in all, the book is a treasure trove listing more than 400 references, in addition to numerous webpage URLs embedded in the texts. The book is designed to help the reader to understand current practices and norms in technical editing, and to help to take action in editing as well as in teaching and educating would-be editors. The audience for this book thus includes editors and teachers, but also writers, researchers and students.